Pharma & Specialty Chemical Standards

Abiraterone, chemically known as 2-methyl-3-(4-methyl-3-oxo-4-(4-nitrophenyl)butyl)chroman-4-one, is a steroidal CYP17A1 inhibitor with molecular formula C21H22N2O5 (molecular weight 378.41 g/mol). It features a chroman ring fused with a 4-ene-3-one system and a nitro-substituted aromatic moiety. Therapeutically utilized in prostate cancer treatment, it exhibits low water solubility and lipophilicity. Its mechanism involves irreversible inhibition of 17α-hydroxylase/C17,20-lyase, suppressing androgen biosynthesis in tumor and adrenal tissues.