Pharma & Specialty Chemical Standards

Atenolol, with the IUPAC name 4-(2-methylpropyl)amino-3-(isopropylamino)-2-hydroxybenzeneethanol, has the molecular formula C₁₄H₂₂N₂O₃ and a molecular weight of 266.34 g/mol. It belongs to the beta-blocker class, characterized by a catecholamine-like structure with a hydroxyl group, isopropylamino moiety, and a methylpropanol side chain. Therapeutically used for hypertension, angina, and arrhythmias, it exhibits water solubility and low lipid solubility. Atenolol selectively antagonizes β₁-adrenergic receptors, reducing cardiac contractility and heart rate by inhibiting sympathetic nervous system activity, thereby decreasing myocardial oxygen demand and systemic vascular resistance.