Pharma & Specialty Chemical Standards

Atmoxitine, with the IUPAC name 4-(2-aminoethyl)phenol, is a substituted phenethylamine derivative. Its molecular formula is C8H11NO2, with a molecular weight of 153.18 g/mol. Structurally, it features a phenyl ring linked to an ethylamine side chain bearing a hydroxyl group, classifying it as an amphetamine analog. Therapeutically, it is under investigation for central nervous system disorders. Key physicochemical properties include moderate water solubility (pKa ~9.5) and a logP of 2.3. Mechanistically, Atmoxitine acts as a norepinephrine-dopamine reuptake inhibitor, modulating monoaminergic neurotransmission via inhibition of presynaptic transporter proteins.