Pharma & Specialty Chemical Standards

Corticosterone, IUPAC name 11β,17α,21-trihydroxypregn-4-ene-3,20-dione (C21H30O5, molecular weight 362.47 g/mol), is a glucocorticoid steroid hormone. Structurally, it features a pregnane backbone with hydroxyl groups at C11β, C17α, and C21, and ketone groups at C3 and C20. It exhibits anti-inflammatory and immunosuppressive properties, utilized in managing inflammatory and autoimmune conditions. A white crystalline solid, it is sparingly soluble in water but soluble in organic solvents. Its mechanism involves binding to glucocorticoid receptors, modulating gene transcription to regulate immune responses and metabolism.