Pharma & Specialty Chemical Standards

Cyanocobalamin, IUPAC name (5,6-dimethylbenzimidazolyl)cobamide(III) cyanide, is a cobalt-containing corrinoid compound with molecular formula C63H88CoN14O14P and molecular weight 1355.37 g/mol. Structurally, it features a corrin ring with a central cobalt ion, a 5,6-dimethylbenzimidazole nucleotide, and a cyanide ligand. Therapeutically, it addresses vitamin B12 deficiency and related hematological/ neurological disorders. It is a red crystalline solid, soluble in water, and stable under acidic conditions. Mechanistically, cyanocobalamin serves as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase, facilitating methyl group transfers and metabolic conversions via cobalt redox activity.