Pharma & Specialty Chemical Standards

Dihydronarwendine (IUPAC: 1,2,3,4,5,6,7,8-octahydro-1,3-dimethoxy-8-(2-methoxyethyl)-2-(methylamino)-9H-carbazole) is a bisbenzylisoquinoline alkaloid with molecular formula C21H27NO4 and molecular weight 357.45 g/mol. Characterized by a tetracyclic core with methoxy and methylamino substituents, it exhibits moderate water solubility and a melting point of ~150°C. Investigated for anti-inflammatory and analgesic properties, its mechanism involves modulation of opioid receptors and inhibition of cyclooxygenase enzymes. Structurally distinct from related alkaloids, it demonstrates low toxicity in preclinical models, though therapeutic applications remain under study.