Pharma & Specialty Chemical Standards

Enalapril, an angiotensin-converting enzyme (ACE) inhibitor, is a prodrug metabolized to enalaprilat. Its IUPAC name is (S)-1-[(2S,3S)-3-mercapto-2-methylpentanoyl]pyrrolidine-2-carboxylic acid, with molecular formula C20H30N2O5S (molecular weight 410.53 g/mol). Structurally, it contains a sulfhydryl group, pyrrolidine ring, and carboxylic acid. Therapeutically, it treats hypertension, heart failure, and post-myocardial infarction. A white, crystalline solid with moderate aqueous solubility, it acts by competitively inhibiting ACE, blocking angiotensin II formation and reducing bradykinin degradation via its sulfhydryl moiety.