Pharma & Specialty Chemical Standards

Enrofloxacin, IUPAC name 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, is a fluoroquinolone antibiotic with molecular formula C19H22FN3O3 and molecular weight 359.38 g/mol. It features a quinoline core substituted with a fluorine at C6, a piperazine ring at C7, and a carboxylic acid group. Therapeutically, it targets Gram-negative and Gram-positive bacteria, particularly in veterinary applications. It exhibits weak basicity, moderate water solubility, and high lipophilicity. Mechanistically, it inhibits bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication and transcription.