Pharma & Specialty Chemical Standards

The formyl group (IUPAC: methanoyl) is a CHO functional group. In formaldehyde (CH₂O, molecular weight 30.03 g/mol), it exists as an aldehyde, featuring a carbonyl group with a hydrogen substituent. Structurally, it exhibits planar geometry and high electrophilicity. Therapeutically, it serves as a crosslinking agent in pharmaceutical excipients and preservatives. Physicochemical properties include high water solubility, volatility, and a low boiling point. Mechanism of action involves nucleophilic attack on the carbonyl carbon, forming Schiff bases with amino groups. Not a drug itself, it is a key intermediate in synthesizing antiseptics and drug conjugates.