1-(3-Bromopropyl)-3-(trifluoromethyl)benzene is a substituted aromatic compound featuring a brominated propyl chain at the para position relative to a trifluoromethyl group on a benzene ring. The 3-bromopropyl substituent introduces a secondary bromide functionality, while the electron-withdrawing trifluoromethyl group (CF3) at the meta position imparts steric and electronic effects influencing reactivity. This impurity arises via alkylation of 3-(trifluoromethyl)benzene with 3-bromopropane or analogous synthetic pathways. It serves as a critical HPLC reference standard for quantifying process-related impurities in parent API synthesis.
On RequestC1=CC(=CC=C1CCCBr)C(F)(F)F
InChI=1S/C10H10BrF3/c11-7-1-2-8-3-5-9(6-4-8)10(12,13)14/h3-6H,1-2,7H2
JWKFKVXKBMORNI-UHFFFAOYSA-N