11-Dehydrocorticosterone is a steroid derivative featuring a pregnane skeleton with a conjugated Ξ4(5) double bond, a 3-keto group, an 11-oxo functionality, a 17Ξ±-hydroxyl, and a 21-hydroxyl. It represents the 11Ξ²-dehydrogenated oxidation product of Corticosterone, substituting the parentβs 11Ξ²-hydroxyl with a carbonyl. This compound serves as a critical HPLC reference standard for quantifying oxidative degradation pathways in Corticosterone-based pharmaceutical formulations.
On RequestC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C
InChI=1S/C21H28O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-16,19,22H,3-8,10-11H2,1-2H3/t14-,15-,16+,19+,20-,21-/m0/s1
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