ABC01422MT

15 epi travoprost

15-epi Travoprost is a stereoisomeric impurity generated via epimerization at the C-15 position of the cyclopentyl ring in the parent prostaglandin analog. This structural inversion alters the spatial configuration of the adjacent hydroxyl group while preserving the fluorinated side chain, ฮณ-lactone core, and ester functionality. The compound exhibits distinct chromatographic and spectroscopic properties compared to the parent drug, necessitating its quantification in API synthesis. It functions as a reference standard for HPLC-based impurity profiling in Travoprost drug substance characterization.

On Request
Molecular Formula C26H35F3O6
Molecular Weight 500.5000
CAS Number 1420791-14-5 โœ“ Verified
PubChem CID 35023509 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Travoprost
Lead Time On Request
IUPAC Name propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate

๐Ÿ“ Synonyms

15-epi Travoprost 1420791-14-5 UNII-NDD23J941F NDD23J941F (Z)-Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid, isopropyl ester 5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-buten-1-yl)cyclopentyl)-, 1-methylethyl ester, (5Z)- Travoprost impurity, 15-epi diastereomer-(USP) Travoprost impurity, 15-epi diastereomer-[USP] TRAVOPROST IMPURITY, 15-EPI DIASTEREOMER-(USP IMPURITY)

๐Ÿ”ฌ Chemical Identifiers

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@@H](COC2=CC=CC(=C2)C(F)(F)F)O)O)O
InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21+,22+,23-,24+/m0/s1
MKPLKVHSHYCHOC-AURHPGDUSA-N

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