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15-S Latanoprost

15-S Latanoprost is the enantiomerically pure 15-S stereoisomer of Latanoprost, featuring a chiral center at the 15-position of the prostaglandin backbone. Its structure includes a 17-phenyl-1,3-propanediol moiety, a conjugated diene system, and a carboxylic acid esterified with a methyl group. This compound arises as a synthetic byproduct during Latanoprost production due to partial inversion at the 15-position. It serves as an HPLC reference standard for quantifying enantiomeric purity in Latanoprost manufacturing processes.

On Request
Molecular Formula C26H40O5
Molecular Weight 432.6000
CAS Number 145773-22-4 ✓ Verified
PubChem CID 10477939 ↗
Purity N/A
Product Type API Impurity
Parent Drug Latanoprost
Lead Time On Request
IUPAC Name propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
Official Reference Standards
Std Catalog # Quantity Price
USP 1357497 ↗ 25 mg USD 1120.00

📝 Synonyms

145773-22-4 15-epi-Latanoprost Latanoprost, (15S)- 15beta-Latanoprost P840K2J2DL UNII-P840K2J2DL 15.BETA.-LATANOPROST LATANOPROST IMPURITY E [EP IMPURITY] 5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3S)-3-hydroxy-5-phenylpentyl)cyclopentyl)-, 1-methylethyl ester, (5Z)- Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3S)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate

🔬 Chemical Identifiers

CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1CC[C@@H](CCC2=CC=CC=C2)O)O)O
InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22-,23-,24+,25-/m1/s1
GGXICVAJURFBLW-SCTZCWPJSA-N

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