2,4-Dimethyl Celecoxib Impurity

2,4-Dimethyl Celecoxib Impurity is a pyrazolyl sulfonamide derivative featuring 2,4-dimethyl substitution on the benzene ring of the parent Celecoxib molecule. The compound retains the core 4-(5-phenyl-3-trifluoromethyl-pyrazol-1-yl)benzenesulfonamide scaffold but incorporates methyl groups at the 2 and 4 positions of the aromatic ring, altering steric and electronic properties. This structural modification renders it a specific byproduct formed during synthetic pathways involving alkylation of Celecoxib precursors. Utilized as an HPLC reference standard for quantifying dimethyl-substituted impurities in Celecoxib API batches.