3-Epi Empagliflozin S Furanose

3-Epi Empagliflozin S Furanose is an epimeric analog of Empagliflozin, featuring an inverted stereochemistry at the C-3 position of the furanose ring. This structural modification alters the spatial orientation of the adjacent hydroxyl and ether functionalities while retaining the 1,5-dihydroxy-4-oxopentyl side chain. The compound exhibits a β-linked glycosidic bond connecting the furanose core to the aromatic scaffold, maintaining the parent drug’s overall pharmacophore. It arises as a stereospecific byproduct during asymmetric synthesis of Empagliflozin, serving as a critical HPLC reference standard for chiral impurity profiling.