3-Hydroxy Nevirapine

3-Hydroxy Nevirapine is a structurally related impurity derived from nevirapine, featuring a hydroxyl group at the 3-position of the pyridine ring. This compound retains the core 2,6-diaminopyridine scaffold and a 4-methoxyphenyl substituent, with the hydroxylation introducing a polar functional group that alters its physicochemical properties. The hydroxyl substitution likely arises via oxidative degradation pathways of the parent drug. This impurity serves as a critical HPLC reference standard for quantifying nevirapine-related impurities in pharmaceutical formulations.