4,5-dichloro Rivaroxaban

4,5-Dichloro Rivaroxaban is a structural analog of Rivaroxaban featuring two chlorine atoms substituted at the 4 and 5 positions of the benzimidazole core. This modification introduces electron-withdrawing chloro substituents, altering the compound's electronic distribution and steric profile compared to the parent anticoagulant. The molecule retains key functional groups, including a nitrile-linked sulfonamide and an esterified phenyl ring, critical for its pharmacophoric interactions. As a synthetic byproduct arising during chlorination steps in Rivaroxaban production, it serves as a reference standard for HPLC-based impurity profiling in active pharmaceutical ingredient (API) quality control.