This compound is a Losartan-related impurity featuring a 1,1'-biphenyl-2-yl substituent appended with a 4-bromomethyl group and a triphenylmethyl (trityl) moiety linked to a 1H-tetrazole ring. The tetrazole nitrogen's tritylation introduces steric bulk, while the bromomethyl substituent introduces halogen reactivity. Structurally, it diverges from Losartan by the trityl substitution and bromination at the meta position of the phenyl ring. Utilized as an HPLC reference standard for quantifying synthetic byproducts in Losartan active pharmaceutical ingredient (API) batches.
On RequestC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N4C(=NN=N4)C5=CC=CC=C5C6=CC=C(C=C6)CBr
InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2
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