ABC01194UN

6-Methyl Resperidone

6-Methyl Resperidone is a structurally modified derivative of Resperidone, characterized by a methyl substitution at the 6-position of the piperidine ring. This compound retains the core benzisoxazole and dibenzothiazepine frameworks of the parent drug but exhibits altered steric and electronic properties due to the methyl group. The molecule contains a tertiary amino functionality, a thiazepine heterocycle, and a fluorinated aromatic ring. Its structural divergence from Resperidone arises from a methylation event during synthetic pathways, leading to reduced pharmacological activity. This compound serves as a critical HPLC reference standard for quantifying process-related impurities in Resperidone formulations.

On Request
Molecular Formula C24H29FN4O2
Molecular Weight 424.5000
CAS Number 1346602-28-5 โœ“ Verified
PubChem CID 71750574 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Resperidone
Lead Time On Request
IUPAC Name 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2,6-dimethyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Official Reference Standards
Std Catalog # Quantity Price
USP 1A11830 โ†— 25 mg USD 975.00

๐Ÿ“ Synonyms

1346602-28-5 6-Methylrisperidone UNII-ZS47CNX0FD ZS47CNX0FD Risperidone specified impurity E [EP] (6RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)ethyl)-2,6-dimethyl-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidin-4-one 4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2,6-dimethyl- RISPERIDONE IMPURITY E [EP IMPURITY] (6RS)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl]-2,6-dimethyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one RISPERIDONE IMPURITY E (EP IMPURITY)

๐Ÿ”ฌ Chemical Identifiers

CC1CCCC2=NC(=C(C(=O)N12)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F)C
InChI=1S/C24H29FN4O2/c1-15-4-3-5-22-26-16(2)19(24(30)29(15)22)10-13-28-11-8-17(9-12-28)23-20-7-6-18(25)14-21(20)31-27-23/h6-7,14-15,17H,3-5,8-13H2,1-2H3
OGYZXUJCZWNPPY-UHFFFAOYSA-N

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