ABC00132AH

Acesulfame potassium impurity B

Acesulfame potassium impurity B is a degradation byproduct arising from the hydrolytic cleavage of the sulfonamide moiety in the parent acesulfame structure. It retains the 6-methyl-1,2,3-oxathiazole core but features a sulfinic acid functional group in place of the terminal amide, resulting in reduced thermal stability. This impurity forms under acidic conditions during synthesis or storage, reflecting a partial oxidation pathway. It serves as a critical HPLC reference standard for quantifying degradation in acesulfame formulations.

On Request
Molecular Formula C4H4ClNO4S
Molecular Weight 197.6000
CAS Number 72827-08-08
PubChem CID 11735746 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Acesulfame
Lead Time On Request
IUPAC Name 5-chloro-6-methyl-2,2-dioxooxathiazin-4-one

๐Ÿ“ Synonyms

72827-08-8 5-Chloro-6-methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide 5-Chloroacesulfame 98K78OBT7F UNII-98K78OBT7F Acesulfame potassium impurity B [EP] 1,2,3-Oxathiazin-4(3H)-one, 5-chloro-6-methyl-, 2,2-dioxide ACESULFAME POTASSIUM IMPURITY B [EP IMPURITY] ACESULFAME POTASSIUM IMPURITY B (EP IMPURITY) Acesulfame Potassium Impurity B

๐Ÿ”ฌ Chemical Identifiers

CC1=C(C(=O)NS(=O)(=O)O1)Cl
InChI=1S/C4H4ClNO4S/c1-2-3(5)4(7)6-11(8,9)10-2/h1H3,(H,6,7)
YVZOKLTZSNJEQX-UHFFFAOYSA-N

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