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Aciclovir EP Impurity F

Aciclovir EP Impurity F is a hydroxylated purine derivative featuring a 2-hydroxyethyl substituent at the 9-position of the guanine core, diverging from the parent drug’s 2-hydroxyethoxymethyl group. Its structure incorporates a five-membered imidazole ring fused to a six-membered pyrimidine ring, with an additional hydroxyl functionality on the side chain. This impurity arises from synthetic pathway branching during acyclic nucleoside formation. It serves as an HPLC reference standard for quantifying process-related impurities in Aciclovir bulk drug substance.

On Request
Molecular Formula C10H13N5O4
Molecular Weight 267.2400
CAS Number 110104-37-5 ✓ Verified
PubChem CID 135443999 ↗
Purity N/A
Product Type API Impurity
Parent Drug Aciclovir
Lead Time On Request
IUPAC Name N-[9-(2-hydroxyethoxymethyl)-6-oxo-1H-purin-2-yl]acetamide
Official Reference Standards
Std Catalog # Quantity Price
USP 1012054 ↗ 50 mg USD 810.00

📝 Synonyms

110104-37-5 N2-Acetylaciclovir N2-Acetyl Acyclovir N2-ACETYL-9-[(2'-HYDROXYETHOXY)METHYL]GUANINE N-(9-((2-Hydroxyethoxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide Aciclovir EP Impurity F N-[9-(2-hydroxyethoxymethyl)-6-oxo-3H-purin-2-yl]acetamide 9-((2-Hydroxyethoxy)methyl)-N2-acetylguanine G007Q63G24 Acetamide, N-(6,9-dihydro-9-((2-hydroxyethoxy)methyl)-6-oxo-1H-purin-2-yl)-

🔬 Chemical Identifiers

CC(=O)NC1=NC2=C(C(=O)N1)N=CN2COCCO
InChI=1S/C10H13N5O4/c1-6(17)12-10-13-8-7(9(18)14-10)11-4-15(8)5-19-3-2-16/h4,16H,2-3,5H2,1H3,(H2,12,13,14,17,18)
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