Atenlol Imp C

Atenlol Imp C is a structurally related impurity of the beta-blocker Atenolol, characterized by a substituted phenylethylamine core with a truncated side chain lacking the terminal methoxy group. Its structure incorporates a primary amine, a hydroxyl group, and an ester functionality, differing from Atenolol by the absence of a methylene bridge and a secondary amide moiety. This compound arises as a synthetic byproduct during Atenolol’s alkylation step, featuring a carbonyl-terminated side chain instead of the parent drug’s amide-linked methoxybenzene. It serves as a critical HPLC reference standard for quantifying process-related impurities in Atenolol drug substance batches.