ABC00232IV

Atorvastatin Related compound C

Atorvastatin Related Compound C is a dimeric derivative of Atorvastatin, formed via coupling of two parent molecules through a calcium-mediated ester linkage. It retains core pyrrole and pyrimidine moieties but incorporates additional fluoride substitutions at the side chains. This impurity arises during synthetic processes involving calcium salts and fluorinated reagents. Structurally, it exhibits a bis-lactone framework with amide-ester hybridization, conferring distinct chromatographic properties. It serves as an HPLC reference standard for quantifying process-specific impurities in Atorvastatin drug substance analysis.

On Request
Molecular Formula C66H66CaF4N4O10
Molecular Weight 1191.3000
CAS Number 693793-53-2 ✓ Verified
PubChem CID 88038664 ↗
Purity N/A
Product Type API Impurity
Parent Drug Atorvastatin
Lead Time On Request
IUPAC Name calcium bis((3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate)
Official Reference Standards
Std Catalog # Quantity Price
USP 1044549 ↗ 20 mg USD 880.00

📝 Synonyms

693793-53-2 Difluoro Atorvastatin Calcium Salt Atorvastatin Related Compound C Calcium (3R,5R)-7-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate Atorvastatin IMpurity C Calcium;(3R,5R)-7-[2,3-bis(4-fluorophenyl)-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate 1H-Pyrrole-1-heptanoic acid, 2,3-bis(4-fluorophenyl)-ss,d-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (ssR,dR)-; Atorvastatin Related Compound C (USP); (3R,5R)-7-[2,3-Bis(4-fluorophenyl)-5-(1-methylethyl)-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt; Fluoroatorvastatin calcium salt Difluoro atorvastatin calcium DifluoroAtorvastatinCalciumSalt SCHEMBL6761197

🔬 Chemical Identifiers

CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)C(=O)NC4=CC=CC=C4.[Ca+2]
InChI=1S/2C33H34F2N2O5.Ca/c2*1-20(2)31-30(33(42)36-25-6-4-3-5-7-25)29(21-8-12-23(34)13-9-21)32(22-10-14-24(35)15-11-22)37(31)17-16-26(38)18-27(39)19-28(40)41;/h2*3-15,20,26-27,38-39H,16-19H2,1-2H3,(H,36,42)(H,40,41);/q;;+2/p-2/t2*26-,27-;/m11./s1
OMNNLAQUOIPKCS-MNSAWQCASA-L

Related Products