ABC00273SB

Beclomethasone 17-mono propionate

Beclomethasone 17-mono propionate is a corticosteroid derivative featuring a 17ฮฑ-hydroxyl group esterified with propionic acid, retaining a 11ฮฒ-hydroxyl and 16ฮฑ-methyl substitution characteristic of the parent glucocorticoid. Its structure lacks the 21-hydroxyl esterification present in beclomethasone dipropionate, resulting in reduced lipophilicity and altered metabolic stability. This compound arises as a synthetic intermediate during the esterification step of beclomethasone production, serving as an HPLC reference standard for impurity profiling in active pharmaceutical ingredient batches.

On Request
Molecular Formula C25H33ClO6
Molecular Weight 465.0000
CAS Number 5534-18-9 โœ“ Verified
PubChem CID 62965 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Beclomethasone
Lead Time On Request
IUPAC Name [(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Official Reference Standards
Std Catalog # Quantity Price
USP 1048543 โ†— 25 mg USD 784.00

๐Ÿ“ Synonyms

Beclomethasone 17-Propionate 5534-18-9 Beclomethasone 17-monopropionate 17-BMP Beclomethasone-17-monopropionate 5BGA9FD55H DTXSID20203899 RefChem:58390 DTXCID00126390 (1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta(a)phenanthren-1-yl propanoate

๐Ÿ”ฌ Chemical Identifiers

CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)Cl)O)C)C)C(=O)CO
InChI=1S/C25H33ClO6/c1-5-21(31)32-25(20(30)13-27)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,26)19(29)12-23(18,25)4/h8-9,11,14,17-19,27,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
OHYGPBKGZGRQKT-XGQKBEPLSA-N

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