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Betamethasone 21-Acetate D3

Betamethasone 21-Acetate D3 is a deuterated analog of the corticosteroid betamethasone, featuring a 21-acetoxy substitution and a deuterium atom at the C3 position. The molecule retains the parent drug's 16ฮฑ-methyl and 11ฮฒ,21-dihydroxy functionalities, with the 21-hydroxyl group esterified to acetic acid. The C3 hydroxyl is substituted with a deuterium isotope, altering its metabolic stability. This compound serves as a critical HPLC reference standard for quantifying C3-deuterated impurities in betamethasone synthesis.

On Request
Molecular Formula C24H31FO6
Molecular Weight 434.5000
CAS Number 987-24-6 โœ“ Verified
PubChem CID 443967 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Betamethasone
Lead Time On Request
IUPAC Name [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Official Reference Standards
Std Catalog # Quantity Price
EP B1030000 โ†— 100 MG EUR 90.00
USP 1067001 โ†— 500 mg USD 297.00

๐Ÿ“ Synonyms

BETAMETHASONE ACETATE Betamethasone 21-acetate 987-24-6 TI05AO53L7 NSC-759196 DTXSID8022668 CHEBI:31275 9-fluoro-11beta,17-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate OSURNIA COMPONENT BETAMETHASONE ACETATE RefChem:54523

๐Ÿ”ฌ Chemical Identifiers

C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)O)F)C
InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
AKUJBENLRBOFTD-QZIXMDIESA-N

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