Boc Velpatasvir intermediate R, R Isomer

Boc Velpatasvir intermediate R, R Isomer is a stereospecific chiral precursor in the synthesis of Velpatasvir, featuring a protected amino group as a tert-butyloxycarbonyl (Boc) derivative. Its structure incorporates two adjacent chiral centers in the R,R configuration, critical for the stereochemical integrity of the parent drug's sulfonamide pharmacophore. The compound serves as a key synthetic intermediate for enantiomeric control during API production, specifically enabling the formation of the pyrazine-linked sulfonamide core. This isomer functions as an HPLC reference standard for impurity profiling in Velpatasvir manufacturing processes.