Cabergoline EP Impurity C (Crude) is a synthetically derived byproduct arising from the incomplete alkylation step during Cabergoline production, characterized by a truncated piperazine ring linked to a substituted dihydroindole moiety, lacking the terminal hydroxyl group present in the parent compound. Its core structure retains the 6,7-dimethoxy-3,4-dihydroisoquinoline scaffold but features an additional methylene bridge at the side chain, altering its stereochemical profile. This impurity serves as a critical HPLC reference standard for quantifying process-related deviations in Cabergoline API batches.
On RequestCCNC(=O)N1C=C2C[C@@H]3[C@H](C[C@H](CN3CC=C)C(=O)N(CCCN(C)C)C(=O)NCC)C4=C2C1=CC=C4
InChI=1S/C29H42N6O3/c1-6-13-33-18-21(27(36)34(28(37)30-7-2)15-10-14-32(4)5)16-23-22-11-9-12-24-26(22)20(17-25(23)33)19-35(24)29(38)31-8-3/h6,9,11-12,19,21,23,25H,1,7-8,10,13-18H2,2-5H3,(H,30,37)(H,31,38)/t21-,23-,25-/m1/s1
MNAGYQBVKIBCGP-GZGNHOFSSA-N