ABC00315QV

Cabergoline EP Impurity C (Crude)

Cabergoline EP Impurity C (Crude) is a synthetically derived byproduct arising from the incomplete alkylation step during Cabergoline production, characterized by a truncated piperazine ring linked to a substituted dihydroindole moiety, lacking the terminal hydroxyl group present in the parent compound. Its core structure retains the 6,7-dimethoxy-3,4-dihydroisoquinoline scaffold but features an additional methylene bridge at the side chain, altering its stereochemical profile. This impurity serves as a critical HPLC reference standard for quantifying process-related deviations in Cabergoline API batches.

On Request
Molecular Formula C29H42N6O3
Molecular Weight 522.7000
CAS Number 126554-50-5 โœ“ Verified
PubChem CID 14380974 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Cabergoline
Lead Time On Request
IUPAC Name (6aR,9R,10aR)-9-N-[3-(dimethylamino)propyl]-4-N-ethyl-9-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9-dicarboxamide

๐Ÿ“ Synonyms

126554-50-5 Cabergoline specified impurity [EP] Cabergoline EP Impurity C N1-Ethylcarbamoyl Cabergoline 5A8SL691O4 (6aR,9R,10aR)-9-N-[3-(dimethylamino)propyl]-4-N-ethyl-9-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9-dicarboxamide (6aR,9R,10aR)-N9-(3-(dimethylamino)propyl)-N4-ethyl-N9-(ethylcarbamoyl)-7-(prop2-enyl)-6a,7,8,9,10,10a-hexahydroindolo(4,3-fg)quinoline-4,9(6H)-dicarboxamide UNII-5A8SL691O4 Ergoline-1,8-dicarboxamide, N8-[3-(dimethylamino)propyl]-N1-ethyl-N8-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8ss)-; (6aR,9R,10aR)-7-allyl-N9-[3-(dimethylamino)propyl]-N4-ethyl-N9-(ethylcarbamoyl)-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9-dicarboxamide; N1-Ethylcarbamoyl Cabergoline DTXSID10155212

๐Ÿ”ฌ Chemical Identifiers

CCNC(=O)N1C=C2C[C@@H]3[C@H](C[C@H](CN3CC=C)C(=O)N(CCCN(C)C)C(=O)NCC)C4=C2C1=CC=C4
InChI=1S/C29H42N6O3/c1-6-13-33-18-21(27(36)34(28(37)30-7-2)15-10-14-32(4)5)16-23-22-11-9-12-24-26(22)20(17-25(23)33)19-35(24)29(38)31-8-3/h6,9,11-12,19,21,23,25H,1,7-8,10,13-18H2,2-5H3,(H,30,37)(H,31,38)/t21-,23-,25-/m1/s1
MNAGYQBVKIBCGP-GZGNHOFSSA-N

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