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Chlarithromycin

Chlorithromycin is a semi-synthetic 14-membered macrolide antibiotic derived from 6-O-methylerythronolide B, featuring a chloro-substituted oxazolidine ring at position 6 and hydroxyl groups at positions 12 and 13. Its structure incorporates a lactone macrocycle with a ketol functionality at C-9, enhancing stability against microbial degradation. As a direct analog of the parent drug, it functions as an HPLC reference standard for macrolide antibiotic quantification in pharmaceutical quality assurance protocols.

On Request
Molecular Formula C38H69NO13
Molecular Weight 748.0000
CAS Number 81103-11-9 ✓ Verified
PubChem CID 84029 ↗
Purity N/A
Product Type API
Parent Drug Chlarithromycin
Lead Time On Request
IUPAC Name (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Official Reference Standards
Std Catalog # Quantity Price
EP Y0000320 ↗ 170 MG EUR 90.00
EP Y0000321 ↗ 10 MG EUR 90.00
USP 1134379 ↗ 100 mg USD 297.00

📝 Synonyms

clarithromycin 81103-11-9 Biaxin 6-O-Methylerythromycin Klaricid Clarithromycine Erythromycin, 6-O-methyl- 6-O-Methylerythromycin a Macladin Klacid

🔬 Chemical Identifiers

CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O
InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
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