ABC00395XU

Citalopram N-Oxide HCl

Citalopram N-Oxide HCl is a piperazine-based N-oxide derivative of the parent SSRI citalopram, featuring a dibenzofazan core with an oxidized nitrogen atom at the piperazine ring. The hydrochloride salt formation protonates the piperazine nitrogen, enhancing water solubility compared to the parent compound. This impurity arises via oxidative metabolism or synthetic pathway side reactions, differing from citalopram by the N-oxide substitution. Utilized as an HPLC reference standard for quantifying process-related impurities in citalopram APIs.

On Request
Molecular Formula C20H22ClFN2O2
Molecular Weight 376.8000
CAS Number 62498-71-9 โœ“ Verified
PubChem CID 10068141 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Citalopram
Lead Time On Request
IUPAC Name 3-[5-cyano-1-(4-fluorophenyl)-3H-2-benzofuran-1-yl]-N,N-dimethylpropan-1-amine oxide;hydrochloride
Official Reference Standards
Std Catalog # Quantity Price
USP 1134288 โ†— 25 mg USD 948.00

๐Ÿ“ Synonyms

62498-71-9 Citalopram N-Oxide Hydrochloride E5WEE9Q3CL Citalopram Related Compound E HCl Salt 3-[5-cyano-1-(4-fluorophenyl)-3H-2-benzofuran-1-yl]-N,N-dimethylpropan-1-amine oxide;hydrochloride 1-(3-(Dimethyloxidoamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile hydrochloride (1:1) 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, N-oxide, monohydrochloride 5-Isobenzofurancarbonitrile, 1-(3-(dimethyloxidoamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, hydrochloride (1:1) 5-Isobenzofurancarbonitrile, 1-(3-(dimethyloxidoamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, monohydrochloride UNII-E5WEE9Q3CL

๐Ÿ”ฌ Chemical Identifiers

C[N+](C)(CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F)[O-].Cl
InChI=1S/C20H21FN2O2.ClH/c1-23(2,24)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-25-20;/h4-9,12H,3,10-11,14H2,1-2H3;1H
IVNQZCHENWHXQU-UHFFFAOYSA-N

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