ABC00424SS

Clotrimazole EP impurity B

Clotrimazole EP Impurity B is a structural isomer of clotrimazole characterized by a 4-chlorophenyl substitution in place of the 2-chlorophenyl moiety. The molecule retains the piperazine and 1H-imidazole core but exhibits altered aromatic substitution patterns. This impurity arises during synthetic processes due to regioselectivity variations in chlorination steps. It serves as an HPLC reference standard for quantifying this specific isomeric impurity in pharmaceutical formulations.

On Request
Molecular Formula C22H17ClN2
Molecular Weight 344.8000
CAS Number 23593-71-7 ✓ Verified
PubChem CID 13073877 ↗
Purity N/A
Product Type API Impurity
Parent Drug Clotrimazole
Lead Time On Request
IUPAC Name 1-[(4-chlorophenyl)-diphenylmethyl]imidazole

📝 Synonyms

23593-71-7 1-((4-Chlorophenyl)diphenylmethyl)-1H-imidazole 1-[(4-Chlorophenyl)diphenylmethyl]-1H-imidazole ZWC2DU38NE CDD-3532 1-((p-Chlorophenyl)diphenylmethyl)imidazole 1H-Imidazole, 1-((4-chlorophenyl)diphenylmethyl)- CLOTRIMAZOLE IMPURITY B [EP IMPURITY] CLOTRIMAZOLE IMPURITY B (EP IMPURITY) RefChem:196882

🔬 Chemical Identifiers

C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)Cl)N4C=CN=C4
InChI=1S/C22H17ClN2/c23-21-13-11-20(12-14-21)22(25-16-15-24-17-25,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-17H
BLNLHAFFGFCSRK-UHFFFAOYSA-N

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