ABC00276WE

Dehydro Benidipine

Dehydro Benidipine is a desaturated analog of Benidipine, featuring a conjugated diene system in place of the parent compound’s dihydropyridine core. This structural modification introduces a trans-double bond between C4 and C5 positions, while retaining nitrophenyl substitution at the 3-position and methoxy groups at the 4- and 6-positions of the pyridine ring. The compound arises as a synthetic byproduct during oxidative dehydrogenation steps in Benidipine production. It serves as a reference standard for HPLC-based impurity profiling in quality control of Benidipine APIs.

On Request
Molecular Formula C28H29N3O6
Molecular Weight 503.5000
CAS Number 118935-44-7
PubChem CID 58893137 β†—
Purity N/A
Product Type API Impurity
Parent Drug Benidipine
Lead Time On Request
IUPAC Name 3-O-(1-benzylpiperidin-3-yl) 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

πŸ“ Synonyms

Dehydro Benidipine 3-(1-Benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate 2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[1-(Phenylmethyl)-3-piperidinyl] Ester; 2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid Methyl 1-(Phenylmethyl)-3-piperidinyl Ester; DH 124; 3-(1-Benzylpiperidin-3-yl) 5-Methyl 2,6-Dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Benidipine Impurity R QRC382V9Y8 SCHEMBL13379606 DH 124 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-[1-(phenylmethyl)-3-piperidinyl] ester 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-piperidinyl ester 3-Methyl 5-[1-(phenylmethyl)-3-piperidinyl] 2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate

πŸ”¬ Chemical Identifiers

CC1=C(C(=C(C(=N1)C)C(=O)OC2CCCN(C2)CC3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC
InChI=1S/C28H29N3O6/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20/h4-7,9-12,15,23H,8,13-14,16-17H2,1-3H3
MVQDCVUGKJYBTK-UHFFFAOYSA-N

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