Desacetyl Cephapirin sodium salt is a deacetylated cephalosporin derivative characterized by a Ξ²-lactam ring fused to a thiazole moiety, with a substituted 4-thiazolidinone core. The sodium salt form arises from deprotonation of the carboxylic acid group, while the absence of the 3-position acetyl group distinguishes it from the parent drug, Cephapirin. This compound retains the key functional groupsβamino, thiol, and Ξ²-lactamβcritical for cephalosporin activity. It serves as a reference standard for HPLC-based impurity profiling in Cephapirin API batches.
On RequestC1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)CSC3=CC=NC=C3)C(=O)[O-])CO.[Na+]
InChI=1S/C15H15N3O5S2.Na/c19-5-8-6-25-14-11(13(21)18(14)12(8)15(22)23)17-10(20)7-24-9-1-3-16-4-2-9;/h1-4,11,14,19H,5-7H2,(H,17,20)(H,22,23);/q;+1/p-1/t11-,14-;/m1./s1
XYXWZYPKYXORJY-GBWFEORMSA-M