ABC00580BA

Desbutyl Dronedarone Hydrochloride

Desbutyl Dronedarone Hydrochloride is a desbutyl derivative of Dronedarone, formed by the removal of the terminal butyl chain from the parent molecule's propylamine side chain. It retains the core structure comprising a bis(aryloxy)propanenitrile scaffold with an amide-linked sulfone bridge and two aromatic rings. The hydrochloride salt form ensures stability and solubility for analytical applications. This compound serves as a critical HPLC reference standard for quantifying desbutyl impurity profiles in Dronedarone drug substance batches.

On Request
Molecular Formula C27H36N2O5S
Molecular Weight 500.7000
CAS Number 141626-35-9 ✓ Verified
PubChem CID 10255437 ↗
Purity N/A
Product Type API Impurity
Parent Drug Dronedarone
Lead Time On Request
IUPAC Name N-[2-butyl-3-[4-[3-(butylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide

📝 Synonyms

Debutyldronedarone 141626-35-9 SR 35021 N-(2-Butyl-3-(4-(3-(butylamino)propoxy)benzoyl)benzofuran-5-yl)methanesulfonamide C3801M93QC SR-35021 UNII-C3801M93QC Methanesulfonamide, N-(2-butyl-3-(4-(3-(butylamino)propoxy)benzoyl)-5-benzofuranyl)- DRONEDARONE METABOLITE H25A RefChem:200375

🔬 Chemical Identifiers

CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCNCCCC
InChI=1S/C27H36N2O5S/c1-4-6-9-25-26(23-19-21(29-35(3,31)32)12-15-24(23)34-25)27(30)20-10-13-22(14-11-20)33-18-8-17-28-16-7-5-2/h10-15,19,28-29H,4-9,16-18H2,1-3H3
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