ABC00518XI

Dihydrodesonide

Dihydrodesonide is a fully hydrogenated derivative of the corticosteroid Desonide, characterized by a saturated A-ring system with retained 11ฮฒ-hydroxy, 16ฮฑ-methyl, and 20-oxo functionalities. The compound exhibits reduced conjugation compared to its parent, featuring a 1ฮฑ,2ฮฑ-dihydro configuration at the A/B ring junction. This impurity arises from incomplete hydrogenation during Desonide synthesis, maintaining key steroidal core substitutions. Serves as a critical HPLC reference standard for quantifying residual hydrogenation byproducts in Desonide active pharmaceutical ingredients.

On Request
Molecular Formula C24H34O6
Molecular Weight 418.5000
CAS Number 638-93-7 โœ“ Verified
PubChem CID 22792150 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Desonide
Lead Time On Request
IUPAC Name (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one

๐Ÿ“ Synonyms

638-93-7 1,2-Dihydrodesonide 16alpha-Hydroxyhydrocortisone 16,17-acetonide PKJ3YPH8PW (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one Dihydrodesonide UNII-PKJ3YPH8PW SCHEMBL2020622 DIHYDRODESONIDE [USP IMPURITY] 11beta,21-Dihydroxy-16alpha,17-isopropylidenedioxy-4-pregnene-3,20-dione

๐Ÿ”ฌ Chemical Identifiers

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CO)C)O
InChI=1S/C24H34O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h9,15-17,19-20,25,27H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1
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