Empagliflozin Intermediat 1

Empagliflozin Intermediat 1 is a bromochlorinated aromatic ester derivative featuring a substituted benzene ring with ortho-oriented bromine and chlorine substituents, linked to a tetrahydrofuran-based ester moiety. Its structure incorporates key functional groups essential for the convergent synthesis of empagliflozin, serving as a critical precursor in the formation of the drug’s core scaffold. This intermediate is specifically employed as an HPLC reference standard for impurity profiling during empagliflozin API process validation.