Empagliflozin

Empagliflozin is a substituted benzylpiperazine derivative featuring a 4-chlorophenyl ring linked via an ether to a piperazine core, which is esterified with a 3-hydroxy-4-methoxybenzoyl moiety. The molecule incorporates a tertiary amine in the piperazine ring and a meta-chloro substituent on the aromatic ring, conferring structural rigidity and hydrophobic character. As the parent drug, it exists in a single enantiomeric form with a fully defined stereochemistry at the piperazine nitrogen. This compound serves as an HPLC reference standard for quantification in pharmaceutical dosage forms.