ABC00703HW

fexofenadine Imp-A

Fexofenadine Imp-A is a dihydroxyphenyl-substituted piperidine derivative arising from oxidative synthetic pathways. It features a 4-(3,4-dihydroxyphenyl) piperidine core linked to a hydroxyethyl ester moiety, differing from the parent drug by an additional ortho-hydroxyl substitution on the aromatic ring. This impurity forms via partial oxidation of the 4-hydroxyphenyl precursor during API synthesis. Serves as a critical HPLC reference standard for quantifying process-related impurities in fexofenadine formulations.

On Request
Molecular Formula C32H37NO4
Molecular Weight 499.6000
CAS Number 76811-98-8 ✓ Verified
PubChem CID 9935699 ↗
Purity N/A
Product Type API Impurity
Parent Drug Fexofenadine
Lead Time On Request
IUPAC Name 2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoic acid
Official Reference Standards
Std Catalog # Quantity Price
EP Y0000751 ↗ 5 MG EUR 90.00
USP 1270388 ↗ 25 mg USD 903.00

📝 Synonyms

76811-98-8 2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid VJS2R7DKY1 UNII-VJS2R7DKY1 2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid EC 616-390-6 Benzeneacetic acid, 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl)-alpha,alpha-dimethyl- 2-(4-(4-(4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL)-1-OXOBUTYL)PHENYL)-2,2-DIMETHYLACETIC ACID 4-(1-OXO-4-(4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL)BUTYL)-.ALPHA.,.ALPHA.-DIMETHYLBENZENEACETIC ACID 4-(4-(4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL)-1-OXOBUTYL)-.ALPHA.,.ALPHA.-DIMETHYLBENZENEACETIC ACID

🔬 Chemical Identifiers

CC(C)(C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)C(=O)O
InChI=1S/C32H37NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28,37H,9,14,19-23H2,1-2H3,(H,35,36)
NGAKDIWPTMPPFP-UHFFFAOYSA-N

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