ABC01557YW

Glycochenodeoxycholic acid sodium salt

Glycochenodeoxycholic acid sodium salt is a conjugated bile acid derivative featuring a 3ฮฑ,7ฮฑ-dihydroxylated steroid nucleus with a glycine moiety linked via an amide bond to the side-chain carboxylate group. This zwitterionic structure, characterized by a sodium counterion, arises from the amidation of chenodeoxycholic acid with glycine, introducing an additional amino functional group. It serves as a critical impurity in the synthesis of chenodeoxycholic acid-based APIs, originating from incomplete conjugation reactions. This compound functions as an HPLC reference standard for quantifying process-related impurities in bile acid pharmaceuticals.

On Request
Molecular Formula C26H42NNaO5
Molecular Weight 471.6000
CAS Number 16564-43-5 โœ“ Verified
PubChem CID 165364823 โ†—
Purity N/A
Product Type API Impurity
Lead Time On Request
IUPAC Name sodium 2-[[(4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetate

๐Ÿ“ Synonyms

Sodium glycochenodeoxycholate 16564-43-5 DTXSID201036173 CHEBI:87818 RefChem:1098796 DTXCID401520382 glycochenodeoxycholic acid sodium salt NSC 681056

๐Ÿ”ฌ Chemical Identifiers

C[C@H](CCC(=O)NCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21?,24+,25+,26-;/m1./s1
AAYACJGHNRIFCT-AYRJTCQJSA-M

Related Products