Ibuprofen Impurity K is a closely related structural analog of Ibuprofen, characterized by the presence of a secondary hydroxyl group at the benzylic position of the 2-methylpropyl side chain, replacing one of the benzylic hydrogens. It retains the propanoic acid moiety and the para-substituted phenyl core. This specific hydroxylation represents an oxidative modification of the isobutyl group found in the parent drug. The compound thus possesses both carboxylic acid and secondary alcohol functionalities within its framework. It serves as an essential reference standard for identifying and quantifying potential oxidative degradation products or metabolites in Ibuprofen formulations.
On RequestC(=O)C1=CC=C(C=C1)C(C(=O)O)C
InChI=1S/C10H10O3/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-7H,1H3,(H,12,13)
IAXYHYOWEQQFMC-UHFFFAOYSA-N