Ibuprofen Methyl ester

Ibuprofen Methyl ester is an ester derivative of the non-steroidal anti-inflammatory drug (NSAID) Ibuprofen. It features the isobutylphenylphenylpropanoic acid core structure of Ibuprofen, with the carboxylic acid moiety esterified by a methyl group. This results in a methyl ester linkage (—COOCH₃) replacing the terminal carboxylic acid (—COOH) present in the parent compound. Structurally, it retains the chiral center at the α-carbon of the propanoic acid chain. This compound serves as a critical reference standard for chromatographic impurity profiling and quantitative analysis of Ibuprofen active pharmaceutical ingredient.