Ipratropium bromide impurity F is a tropane-derived quaternary ammonium compound featuring an 8ฮฑ-hydroxytropan-8ฮฒ-yl moiety linked via a butylene bridge to a dimethylaminoethyl group, substituted with a bromide counterion and a ฮณ-hydroxybutyrate ester. It represents a side-chain hydroxylation byproduct formed during synthetic oxidation steps, retaining the core tropane scaffold but incorporating a carboxylate ester and tertiary amine. This impurity functions as an HPLC reference standard for monitoring oxidative degradation pathways in ipratropium bromide formulations.
On Request| Std | Catalog # | Quantity | Price |
|---|---|---|---|
| EP | I0360000 โ | 100 MG | EUR 90.00 |
| USP | 1347507 โ | 200 mg | USD 314.00 |
CC(C)[N+]1([C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)C.O.[Br-]
InChI=1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18?,19?,21?;;
KEWHKYJURDBRMN-XFQAGIBXSA-M