Levobupivacaine Impurity C is a structurally related degradation byproduct arising from the oxidative cleavage of the propylamide side chain in levobupivacaine. It retains the benzoyl moiety and tert-butylamine core but lacks the terminal propyl group, featuring a conjugated amide and aromatic ring system. This impurity exhibits distinct UV absorption maxima due to the extended conjugation and serves as a critical HPLC reference standard for quantifying degradation pathways in levobupivacaine formulations under accelerated stability testing.
On RequestCC1=C(C(=CC=C1)C)N2CCCC=CC2=O
InChI=1S/C14H17NO/c1-11-7-6-8-12(2)14(11)15-10-5-3-4-9-13(15)16/h4,6-9H,3,5,10H2,1-2H3
MOZRUAQMNSSBSM-UHFFFAOYSA-N