ABC00977CI

Mupirocin Calcium EP impurity F

Mupirocin Calcium EP impurity F is a calcium salt derivative of the cyclic depsipeptide mupirocin, characterized by a truncated macrocyclic lactone ring and a modified side chain. It retains the core 2-pyrrolidinone motif but exhibits a linearized ester linkage at the C-terminus, replacing the parent drug's cyclic structure. This impurity arises via partial hydrolysis of the native lactone ring during synthesis or storage. Its distinct functional groups include a free carboxylic acid and a calcium-coordinated hydroxyl moiety, conferring altered solubility and chromatographic behavior. This compound serves as a critical HPLC reference standard for quantifying process-related impurities in mupirocin active pharmaceutical ingredients.

On Request
Molecular Formula C24H40O9
Molecular Weight 472.6000
CAS Number 167842-64-0 โš  Unverified
PubChem CID 72941720 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Mupirocin
Lead Time On Request
IUPAC Name 7-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxyheptanoic acid

๐Ÿ“ Synonyms

Pseudomonic Acid F DE(8-carboxyoctyl)6-carboxyhexylmupirocin UNII-62A2FN8SE0 62A2FN8SE0 Mupirocin calcium impurity F [EP] MUPIROCIN IMPURITY F [EP IMPURITY] MUPIROCIN CALCIUM IMPURITY F [EP IMPURITY] MUPIROCIN IMPURITY F (EP IMPURITY) MUPIROCIN CALCIUM IMPURITY F (EP IMPURITY) RefChem:200366

๐Ÿ”ฌ Chemical Identifiers

C[C@H]([C@H]1[C@@H](O1)C[C@H]2CO[C@H]([C@@H]([C@@H]2O)O)C/C(=C/C(=O)OCCCCCCC(=O)O)/C)[C@H](C)O
InChI=1S/C24H40O9/c1-14(11-21(28)31-9-7-5-4-6-8-20(26)27)10-18-23(30)22(29)17(13-32-18)12-19-24(33-19)15(2)16(3)25/h11,15-19,22-25,29-30H,4-10,12-13H2,1-3H3,(H,26,27)/b14-11+/t15-,16-,17-,18-,19-,22+,23-,24-/m0/s1
MIVFEJHUAUQOLX-XUUZYBQDSA-N

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