ABC01274FG

N-Monodesmethyl sibutramine hydrochloride

N-Monodesmethyl sibutramine hydrochloride is a structurally related impurity derived from sibutramine via N-demethylation, retaining a chloroethyl side chain and aromatic amine functionality. Its secondary amine moiety features a single methyl substitution, distinguishing it from the parent compound’s dimethylated nitrogen. The hydrochloride salt form ensures stability and solubility for analytical applications. This compound serves as a critical HPLC reference standard for quantifying process-related impurities in sibutramine formulations.

On Request
Molecular Formula C16H25Cl2N
Molecular Weight 302.3000
CAS Number 84467-94-7 ✓ Verified
PubChem CID 13083195 ↗
Purity N/A
Product Type API Impurity
Parent Drug Sibutramine
Lead Time On Request
IUPAC Name 1-[1-(4-chlorophenyl)cyclobutyl]-N,3-dimethylbutan-1-amine;hydrochloride
Official Reference Standards
Std Catalog # Quantity Price
USP 1612889 ↗ 20 mg USD 822.00

📝 Synonyms

84467-94-7 Desmethylsibutramine hydrochloride N-Desmethylsibutramine hydrochloride UNII-L01HKI9MTT L01HKI9MTT mono-Desmethylsibutramine hydrochloride BTS 54-354 BTS-54-354 CYCLOBUTANEMETHANAMINE, 1-(4-CHLOROPHENYL)-N-METHYL-.ALPHA.-(2-METHYLPROPYL)-, HYDROCHLORIDE CYCLOBUTANEMETHANAMINE, 1-(4-CHLOROPHENYL)-N-METHYL-.ALPHA.-(2-METHYLPROPYL)-, HYDROCHLORIDE (1:1)

🔬 Chemical Identifiers

CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)NC.Cl
InChI=1S/C16H24ClN.ClH/c1-12(2)11-15(18-3)16(9-4-10-16)13-5-7-14(17)8-6-13;/h5-8,12,15,18H,4,9-11H2,1-3H3;1H
OUVFHVJVFLFXPQ-UHFFFAOYSA-N

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