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Norethindrone EP Impurity F

Norethindrone EP Impurity F is a 19-nor-17ฮฑ-pregnane derivative featuring a 3-keto group and a 17ฮฑ-pregnenolone skeleton, with a modified side chain containing a terminal cyclopropane ring. This impurity arises via retro-aldol cleavage of the parent norethindrone, resulting in a truncated C13โ€“C20 fragment retaining the 17-keto functionality. It serves as a critical HPLC reference standard for quantifying process-related impurities in norethindrone synthesis.

On Request
Molecular Formula C22H30O2
Molecular Weight 326.5000
CAS Number 96487-85-3 โœ“ Verified
PubChem CID 90477801 โ†—
Purity N/A
Product Type API Impurity
Parent Drug Norethindrone
Lead Time On Request
IUPAC Name (8R,9S,10R,13S,14S,17R)-3-ethoxy-17-ethynyl-13-methyl-2,7,8,9,10,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-ol

๐Ÿ“ Synonyms

96487-85-3 Norethindrone 3-Ethyl Ether UWL75G8KB6 Norethisterone impurity F [EP] DTXSID901021161 (17alpha)-3-Ethoxy-19-norpregna-3,5-dien-20-yn-17-ol 19-Nor-17alpha-pregna-3,5-dien-20-yn-17-ol, 3-ethoxy- 19-Norpregna-3,5-dien-20-yn-17-ol, 3-ethoxy-, (17alpha)- NORETHISTERONE IMPURITY F [EP IMPURITY] 19-NOR-17.ALPHA.-PREGNA-3,5-DIEN-20-YN-17-OL, 3-ETHOXY-

๐Ÿ”ฌ Chemical Identifiers

CCOC1=CC2=CC[C@@H]3[C@@H]([C@H]2CC1)CC[C@]4([C@H]3CC[C@]4(C#C)O)C
InChI=1S/C22H30O2/c1-4-22(23)13-11-20-19-8-6-15-14-16(24-5-2)7-9-17(15)18(19)10-12-21(20,22)3/h1,6,14,17-20,23H,5,7-13H2,2-3H3/t17-,18+,19+,20-,21-,22-/m0/s1
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