O-Desmethyl galantamine

O-Desmethyl galantamine is a tropane alkaloid derivative characterized by a bicyclic tropane skeleton substituted with a hydroxyl group at the oxygen site and an amide functionality at the nitrogen. This compound represents a demethylated analog of galantamine, lacking the methyl group on the oxygen atom of the parent structure, which alters its pharmacophoric properties. The absence of the methyl substituent introduces a polar hydroxyl moiety, enhancing hydrogen bonding potential while reducing steric bulk. It serves as a critical HPLC reference standard for quantifying process-related impurities in galantamine synthesis.