Orlistat related compound B

Orlistat related compound B is a synthetic byproduct arising from the partial cyclization of intermediates in the Orlistat synthesis pathway. It features a substituted piperidinyl moiety linked to a γ-lactam core, with a branched alkoxy side chain containing two ester functionalities. This compound lacks the aromatic fluorophenyl and chlorophenyl substituents present in the parent drug, resulting in distinct hydrophobic and hydrogen-bonding profiles. It serves as a critical HPLC reference standard for quantifying process-related impurities in Orlistat active pharmaceutical ingredients.