ABC01072CJ

Palonosetron Related Compound A

Palonosetron Related Compound A is a structurally analogous impurity derived from the parent drug, characterized by a substituted piperazine ring connected to a pyridine core. The absence of a fluorine atom at the 2-position of the indole moiety, replaced by a methylene group, distinguishes it from Palonosetron. This compound features a 4-(4-methylpiperazin-1-yl)phenol substructure linked via an ethyl bridge to the pyridine ring. It serves as a critical HPLC reference standard for quantifying process-related impurities in Palonosetron API synthesis.

On Request
Molecular Formula C19H24N2O2
Molecular Weight 312.4000
CAS Number 813425-83-1 ✓ Verified
PubChem CID 46782681 ↗
Purity N/A
Product Type API Impurity
Parent Drug Palonosetron
Lead Time On Request
IUPAC Name (3aS)-2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
Official Reference Standards
Std Catalog # Quantity Price
USP 1492222 ↗ 15 mg USD 939.00

📝 Synonyms

Palonosetron N-Oxide 813425-83-1 MIV4QW9F6J UNII-MIV4QW9F6J PALONOSETRON METABOLITE M9 (3aS)-1-Oxo-2-((3S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo(de)isoquinoline 1-oxide 1H-Benz(de)isoquinolin-1-one, 2,3,3a,4,5,6-hexahydro-2-((3S)-1-oxido-1-azabicyclo(2.2.2)oct-3-yl)-, (3aS)- 1H-Benz[de]isoquinolin-1-one, 2,3,3a,4,5,6-hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-, (3aS)- RefChem:202495 PALONOSETRON METABOLITE (N-OXIDE-PALONOSETRON)

🔬 Chemical Identifiers

C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4C[N+]5(CCC4CC5)[O-]
InChI=1S/C19H24N2O2/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-20(19)17-12-21(23)9-7-13(17)8-10-21/h2,4,6,13,15,17H,1,3,5,7-12H2/t13?,15-,17-,21?/m1/s1
IQQIWUDYGYXXEA-BGAFOXLKSA-N

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