ABC00218QB

parahydroxy atorvastatin calcium

Parahydroxy atorvastatin calcium is a calcium salt of a hydroxylated atorvastatin derivative, featuring a hydroxyl substitution at the para position of the phenyl ring. This impurity arises from oxidative metabolism or synthetic pathways, introducing a polar hydroxyl group adjacent to the pyrrole and hydrogenated benzene moieties. The calcium counterion stabilizes the zwitterionic structure, enhancing solubility. It serves as an HPLC reference standard for quantifying process-related impurities in atorvastatin formulations.

On Request
Molecular Formula C33H34CaFN2O6+
Molecular Weight 613.7000
CAS Number 1263176-34-6 ✓ Verified
PubChem CID 45358923 ↗
Purity N/A
Product Type API Impurity
Parent Drug Atorvastatin
Lead Time On Request
IUPAC Name calcium (3R,5R)-7-[2-(4-fluorophenyl)-4-[(4-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate

📝 Synonyms

1263176-34-6 4-Hydroxy Atorvastatin Hemicalcium Salt (>90%) (ssR,dR)-2-(4-Fluorophenyl)-ss,d-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Hemicalcium Salt; p-Hydroxyatorvastatin Hemicalcium Salt 4-Hydroxy atorvastatin hemicalcium salt PD061051

🔬 Chemical Identifiers

CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)O.[Ca+2]
InChI=1S/C33H35FN2O6.Ca/c1-20(2)31-30(33(42)35-24-12-14-25(37)15-13-24)29(21-6-4-3-5-7-21)32(22-8-10-23(34)11-9-22)36(31)17-16-26(38)18-27(39)19-28(40)41;/h3-15,20,26-27,37-39H,16-19H2,1-2H3,(H,35,42)(H,40,41);/q;+2/p-1/t26-,27-;/m1./s1
PXVKCBJKCBMVNK-CNZCJKERSA-M

Related Products