Prothioconazole-4-hydroxydesthio

Prothioconazole-4-hydroxydesthio is a synthetic derivative of the triazole fungicide prothioconazole, featuring a 4-hydroxyl substitution on the triazole ring and a desulfurized thiazole moiety replaced by an oxo group. The structure retains two chloro substituents on the phenyl ring and a triazole core, with the hydroxyl group introducing a polar functional handle. This compound arises via oxidative degradation of prothioconazole, reflecting a specific metabolic pathway involving hydroxylation and sulfur oxidation. It serves as a critical HPLC reference standard for quantifying prothioconazole impurities in pharmaceutical and agrochemical formulations.